Measles Outbreak in Previously Immunized Children, Florida, US|
Posted by vaccinesme on Wednesday, January, 21 2009 and filed under Articles
Key topics: Measles Outbreak Measles
Robert O. Baratta M.D., Myrna C. Ginter M.D., Morris A. Price M.D., James W. Walker M.D., Richard G. Skinner M.D., E. Charlton Prather M.D., and Joseph K. David M.D.
Division of health, Florida Department of health and Rehabilitative Services, Jacksonville, the Consolidated health Department, City of Jacksonville, the Jacksonville Hospitals Educational Program, Incorporated, and the National Communicable disease Center, health Services and mental health Administration, Public health Service, U.S. Department of health, Education and Welfare, Atlanta, Georgia
Measles (Rubeola) in Previously Immunized Children. PEDIATRICS Vol. 46 No. 3 September 1970, pp. 397-402.
Within a 3-month countywide epidemic of measles in Jacksonville, Florida, 28 cases occurring among a kindergarten enrollment of 145 were carefully studied since 25 of these children had been previously immunized with a live, attenuated measles virus vaccine and immune globulin. Nineteen children had been vaccinated prior to their first birthday. Six children were vaccinated at 13 to 20 months of age. The median measles (rubeola) hemagglutination-inhibition (HI) antibody titer in sera of five convalescent patients immunized before their first birthday was 1:320 and for complement fixation it was 1:128. Sera from nine classmates who did not contract the disease showed a median HI antibody of 1:40 and a median complement fixing antibody (CF) of 1:16. Six had been vaccinated before their first birthday.
That's a 90% "vaccine failure" as they call it, and the vaccine contained a live attenuated (weakened) virus. And there was little difference in the severity of the disease between the vaccinated and unvaccinated.