Friday, 19 July 2019    HomeAbout UsContact Us    









You are here: Home Articles


Two Successive Outbreaks Of Mumps In Nova Scotia Among Vaccinated Adolescents And Young Adults
Posted by vaccinesme, in Articles
Topics: Vaccine Failure Mumps Outbreak

  Mail To Friend    Printer Friendly Bookmark and Share

Gaynor Watson-Creed, Andrea Saunders, Jeffrey Scott, Luis Lowe, Janice Pettipas, and Todd F. Hatchette. Two Successive Outbreaks Of mumps In Nova Scotia Among Vaccinated Adolescents And Young Adults. CMAJ. 2006 August 29; 175(5): 483488.

Two recent outbreaks in Nova Scotia were investigated by public health officials. Cases were defined by laboratory confirmation of infection (i.e., isolation of mumps virus by culture) or clinical diagnosis in people epidemiologically linked to a laboratory-confirmed case. The people infected were interviewed to determine possible links and to identify contacts. Mumps virus was cultured from urine and throat specimens, identified via reverse-transcriptase polymerase chain reaction (RT-PCR) and subjected to phylogenetic analysis to identify the origin of the strain.

Results. The first outbreak involved 13 high-school students (median age 14 yr): 9 who had previously received 2 doses of measlesmumpsrubella vaccine (MMR) and 4 who received a single dose. The second outbreak comprised 19 cases of mumps among students and some staff at a local university (median age 23 yr), of whom 18 had received only 1 dose of MMR (the other received a second dose). The viruses identified in the outbreaks were phylogenetically similar and belonged to a genotype commonly reported in the UK. The virus from the second outbreak is identical to the strain currently circulating in the UK and United States.

Interpretation. The predominance in these outbreaks of infected people of university age not only highlights an environment with potential for increased transmission but also raises questions about the efficacy of the MMR vaccine. The people affected may represent a lost cohort who do not have immunity from natural mumps infection and were not offered a 2-dose schedule. Given the current level of mumps activity around the world, clinicians should remain vigilant for symptoms of mumps.


Link to this article:   Show: HTML LinkFull LinkShort Link
Share or Bookmark this page: You will need to have an account with the selected service in order to post links or bookmark this page.

                 
  
Subscribe via RSS or email:
Follow us through RSS or email. Click the RSS icon to subscribe to our feed.

     
  

Related Articles:
Add a Comment
You must be registered and logged in to comment.







Topics
Basics
Vaccines
Nutrition
Articles
News

Latest Articles
Effective or Ineffective: Attribute Framing and the Human Papillomavirus (HPV) Vaccine
CNS Demyelination and Quadrivalent HPV Vaccination
Pertussis Infection in Fully Vaccinated Children in Day-Care Centers, Israel
Chemoprevention Trial of Human Hepatitis With Selenium Supplementation in China
Protective Role of Selenium Against Hepatitis B Virus and Primary Liver Cancer in Qidong
An Increase in Selenium Intake Improves Immune Function and Poliovirus Handling in Adults With Marginal Selenium Status
Nutritional and Food Protection Against Epidemic Emerging Neuropathy. Epidemiological Findings in the Unique Disease-Free Urban Area of Cuba
Diphtheria-Tetanus-Pertussis Vaccine Administered Simultaneously With Measles Vaccine Is Associated With Increased Morbidity and Poor Growth in Girls
Children Vaccinated With MMR and Higher Risk of Multiple Sclerosis
A Possible Central Mechanism in Autism Spectrum Disorders

Pages
No pages found.

Most Popular
What Is Vaccine Failure?
Antibody Response To Vaccine Does Not Equal Immunity or Protection
Protective Effect of Childhood Measles Against Degenerative Diseases in Later Life
Measles Outbreak in Previously Immunized Children, Florida, US
Discontinuation of BCG Vaccine in Japan Leads To Significant Drop in Type 2 Diabetes
The Myth Of Vaccines Causing 20th Century Mortality Decline: Excellent Paper by Mckinlay and Mckinlay
Explaining the Reemergence of Pertussis in Vaccinated Populations
Explosive School-Based Measles Outbreak in Vaccinated Students - Finland
BCG (Tuberculosis) Vaccine Induced Inflammation Linked to Type 2 Diabetes Epidemic
Graphical Evidence: Vaccination Did Not Save Populations - Data From Australia

Archives (View more)
2011 • December
2011 • October
2010 • February
2009 • June
2009 • May
2009 • April
2009 • March
2009 • February
2009 • January


Popular Topics
mortality declinemeaslesmortality ratesmeasles outbreaksVitamin AVitamin Cmeasles deathsmeasles outbreakvaccine failuresecondary vaccine failuremumpsMMRmumps outbreakrubini strainantibodiesantibodymumps vaccineaseptic meningitisenterovirusechovirusurabe strainrubellapregnancyautismparkinsons diseasemeasles vaccineadverse reactionsGuillain-Barre Syndromebrain injurydeathGeorge Fishervaccine deathvaccine compensationpoliovaccine damagereverse transcriptaseretroviruseschicken poxvaricellapertussiswhooping coughDTPdiptheriatetanusdiabetesBCGHIBHemophilus BasthmaallergiesmercurythimerosalgardasilHPVASDBailey BanksHerd Immunitypneumoniaprevnarpneumococcalotitispediacelpsoriasisflu vaccineHepatitis BHepatitis APseudolymphomaaluminium hydroxideallergyatopyCRSmeningitisinfectionsvaccination policyvaccination scienceOPVoral polio vaccineseroconversionvaccine marketingcervical cancerinfluenzaDPTchickenpoxvaccinationimmunizationnatural immunityvaccine efficacyreinfectionmultiple sclerosisprimary vaccine failureGuillain-BarreSIDSsudden deatharthritisadjuvantsaluminiumchronic fatigueexcitotoxinsimmunoexcitotoxinsSelenium
Copyright © 2019 . All rights reserved. RSSTagsPrivacyLegal and Terms of UseSitemap